The analysis shows that loss of UBE3A expression in the cortex a, hippocampus b, cerebellum c and striatum d of these mice is comparable to mice in which the Ube3a gene is absent throughout development embryonic deletion N 3 per genotype cost cytotec without insurance ICSI intracytoplasmic sperm injection a procedure in which a single sperm is injected directly into an egg; this procedure is most commonly used to overcome male infertility problems